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cd47 proteintech  (Proteintech)


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    Proteintech cd47 proteintech
    MYC promotes M2 macrophage differentiation by regulating <t>CD47</t> expression. A Immunofluorescence showed the intercellular localization of MYC and CD47. B-C After knocking down MYC, MYC and CD47 protein and mRNA levels in the cells changed. D The JASPAR database predicted potential MYC-binding sites on the CD47 promoters. E MYC binding to the CD47 promoter was evaluated by ChIP-qPCR assay. F Process of cell co-culture. G Expression levels of the marker gene in M1 and M2 macrophages. H The interaction between SIRPα and CD47 was validated by the Co-IP assay. I-J Differential genes and gene enrichment results were shown. K-L Western blot results showed changes in PI3K/AKT protein expression levels. M Expression levels of the marker gene in M1 and M2 macrophages
    Cd47 Proteintech, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 89 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cd47 proteintech/product/Proteintech
    Average 95 stars, based on 89 article reviews
    cd47 proteintech - by Bioz Stars, 2026-06
    95/100 stars

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    1) Product Images from "MYC promotes the progression of prostate cancer by regulating CD47 to induce an immunosuppressive microenvironment"

    Article Title: MYC promotes the progression of prostate cancer by regulating CD47 to induce an immunosuppressive microenvironment

    Journal: Cellular and Molecular Life Sciences: CMLS

    doi: 10.1007/s00018-026-06109-0

    MYC promotes M2 macrophage differentiation by regulating CD47 expression. A Immunofluorescence showed the intercellular localization of MYC and CD47. B-C After knocking down MYC, MYC and CD47 protein and mRNA levels in the cells changed. D The JASPAR database predicted potential MYC-binding sites on the CD47 promoters. E MYC binding to the CD47 promoter was evaluated by ChIP-qPCR assay. F Process of cell co-culture. G Expression levels of the marker gene in M1 and M2 macrophages. H The interaction between SIRPα and CD47 was validated by the Co-IP assay. I-J Differential genes and gene enrichment results were shown. K-L Western blot results showed changes in PI3K/AKT protein expression levels. M Expression levels of the marker gene in M1 and M2 macrophages
    Figure Legend Snippet: MYC promotes M2 macrophage differentiation by regulating CD47 expression. A Immunofluorescence showed the intercellular localization of MYC and CD47. B-C After knocking down MYC, MYC and CD47 protein and mRNA levels in the cells changed. D The JASPAR database predicted potential MYC-binding sites on the CD47 promoters. E MYC binding to the CD47 promoter was evaluated by ChIP-qPCR assay. F Process of cell co-culture. G Expression levels of the marker gene in M1 and M2 macrophages. H The interaction between SIRPα and CD47 was validated by the Co-IP assay. I-J Differential genes and gene enrichment results were shown. K-L Western blot results showed changes in PI3K/AKT protein expression levels. M Expression levels of the marker gene in M1 and M2 macrophages

    Techniques Used: Expressing, Immunofluorescence, Binding Assay, ChIP-qPCR, Co-Culture Assay, Marker, Co-Immunoprecipitation Assay, Western Blot

    The role of macrophages in modulating the functional behaviors of PCa cells. A Cells were co-cultured for display. B-C The proportion of CD8 + T cells was measured by flow cytometry. D Transwell assay results showed the effect of MYC and CD47 expression on the invasion ability of PCa cells. E. EdU assay results showed the effect of MYC and CD47 expression levels on the proliferation of PCa cells. F-G The results of the colony-formation and wound-healing experiments showed the effects of MYC and CD47 expression levels on the proliferation and migration of PCa cells. H Representative multiplex immunofluorescence staining images depict MYC, CD47, CD8 + T and M2 cell in PCa tissues
    Figure Legend Snippet: The role of macrophages in modulating the functional behaviors of PCa cells. A Cells were co-cultured for display. B-C The proportion of CD8 + T cells was measured by flow cytometry. D Transwell assay results showed the effect of MYC and CD47 expression on the invasion ability of PCa cells. E. EdU assay results showed the effect of MYC and CD47 expression levels on the proliferation of PCa cells. F-G The results of the colony-formation and wound-healing experiments showed the effects of MYC and CD47 expression levels on the proliferation and migration of PCa cells. H Representative multiplex immunofluorescence staining images depict MYC, CD47, CD8 + T and M2 cell in PCa tissues

    Techniques Used: Functional Assay, Cell Culture, Flow Cytometry, Transwell Assay, Expressing, EdU Assay, Migration, Multiplex Assay, Immunofluorescence, Staining



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    MYC promotes M2 macrophage differentiation by regulating <t>CD47</t> expression. A Immunofluorescence showed the intercellular localization of MYC and CD47. B-C After knocking down MYC, MYC and CD47 protein and mRNA levels in the cells changed. D The JASPAR database predicted potential MYC-binding sites on the CD47 promoters. E MYC binding to the CD47 promoter was evaluated by ChIP-qPCR assay. F Process of cell co-culture. G Expression levels of the marker gene in M1 and M2 macrophages. H The interaction between SIRPα and CD47 was validated by the Co-IP assay. I-J Differential genes and gene enrichment results were shown. K-L Western blot results showed changes in PI3K/AKT protein expression levels. M Expression levels of the marker gene in M1 and M2 macrophages
    Cd47 Proteintech, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    cd47 monoclonal antibody cat no 66304 1 ig proteintech  (Proteintech)
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    MYC promotes M2 macrophage differentiation by regulating <t>CD47</t> expression. A Immunofluorescence showed the intercellular localization of MYC and CD47. B-C After knocking down MYC, MYC and CD47 protein and mRNA levels in the cells changed. D The JASPAR database predicted potential MYC-binding sites on the CD47 promoters. E MYC binding to the CD47 promoter was evaluated by ChIP-qPCR assay. F Process of cell co-culture. G Expression levels of the marker gene in M1 and M2 macrophages. H The interaction between SIRPα and CD47 was validated by the Co-IP assay. I-J Differential genes and gene enrichment results were shown. K-L Western blot results showed changes in PI3K/AKT protein expression levels. M Expression levels of the marker gene in M1 and M2 macrophages
    Cd47 Monoclonal Antibody Cat No 66304 1 Ig Proteintech, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cd47 monoclonal antibody cat no 66304 1 ig proteintech/product/Proteintech
    Average 95 stars, based on 1 article reviews
    cd47 monoclonal antibody cat no 66304 1 ig proteintech - by Bioz Stars, 2026-06
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    Image Search Results


    MYC promotes M2 macrophage differentiation by regulating CD47 expression. A Immunofluorescence showed the intercellular localization of MYC and CD47. B-C After knocking down MYC, MYC and CD47 protein and mRNA levels in the cells changed. D The JASPAR database predicted potential MYC-binding sites on the CD47 promoters. E MYC binding to the CD47 promoter was evaluated by ChIP-qPCR assay. F Process of cell co-culture. G Expression levels of the marker gene in M1 and M2 macrophages. H The interaction between SIRPα and CD47 was validated by the Co-IP assay. I-J Differential genes and gene enrichment results were shown. K-L Western blot results showed changes in PI3K/AKT protein expression levels. M Expression levels of the marker gene in M1 and M2 macrophages

    Journal: Cellular and Molecular Life Sciences: CMLS

    Article Title: MYC promotes the progression of prostate cancer by regulating CD47 to induce an immunosuppressive microenvironment

    doi: 10.1007/s00018-026-06109-0

    Figure Lengend Snippet: MYC promotes M2 macrophage differentiation by regulating CD47 expression. A Immunofluorescence showed the intercellular localization of MYC and CD47. B-C After knocking down MYC, MYC and CD47 protein and mRNA levels in the cells changed. D The JASPAR database predicted potential MYC-binding sites on the CD47 promoters. E MYC binding to the CD47 promoter was evaluated by ChIP-qPCR assay. F Process of cell co-culture. G Expression levels of the marker gene in M1 and M2 macrophages. H The interaction between SIRPα and CD47 was validated by the Co-IP assay. I-J Differential genes and gene enrichment results were shown. K-L Western blot results showed changes in PI3K/AKT protein expression levels. M Expression levels of the marker gene in M1 and M2 macrophages

    Article Snippet: Finally, the sections were counterstained with DAPI for 10 min, washed, and mounted with an anti-fade mounting medium. (Myc: Abcam, ab32072; CD47: Proteintech, 20305-1-AP; CD206: Cell Signaling Technology, 24595 T; CD8: Abcam, ab237709).

    Techniques: Expressing, Immunofluorescence, Binding Assay, ChIP-qPCR, Co-Culture Assay, Marker, Co-Immunoprecipitation Assay, Western Blot

    The role of macrophages in modulating the functional behaviors of PCa cells. A Cells were co-cultured for display. B-C The proportion of CD8 + T cells was measured by flow cytometry. D Transwell assay results showed the effect of MYC and CD47 expression on the invasion ability of PCa cells. E. EdU assay results showed the effect of MYC and CD47 expression levels on the proliferation of PCa cells. F-G The results of the colony-formation and wound-healing experiments showed the effects of MYC and CD47 expression levels on the proliferation and migration of PCa cells. H Representative multiplex immunofluorescence staining images depict MYC, CD47, CD8 + T and M2 cell in PCa tissues

    Journal: Cellular and Molecular Life Sciences: CMLS

    Article Title: MYC promotes the progression of prostate cancer by regulating CD47 to induce an immunosuppressive microenvironment

    doi: 10.1007/s00018-026-06109-0

    Figure Lengend Snippet: The role of macrophages in modulating the functional behaviors of PCa cells. A Cells were co-cultured for display. B-C The proportion of CD8 + T cells was measured by flow cytometry. D Transwell assay results showed the effect of MYC and CD47 expression on the invasion ability of PCa cells. E. EdU assay results showed the effect of MYC and CD47 expression levels on the proliferation of PCa cells. F-G The results of the colony-formation and wound-healing experiments showed the effects of MYC and CD47 expression levels on the proliferation and migration of PCa cells. H Representative multiplex immunofluorescence staining images depict MYC, CD47, CD8 + T and M2 cell in PCa tissues

    Article Snippet: Finally, the sections were counterstained with DAPI for 10 min, washed, and mounted with an anti-fade mounting medium. (Myc: Abcam, ab32072; CD47: Proteintech, 20305-1-AP; CD206: Cell Signaling Technology, 24595 T; CD8: Abcam, ab237709).

    Techniques: Functional Assay, Cell Culture, Flow Cytometry, Transwell Assay, Expressing, EdU Assay, Migration, Multiplex Assay, Immunofluorescence, Staining